Addressing unmet needs in oncology

Targeted therapeutics, patient selection,
and execution that drives value.

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Lead Oncology Products

MGCD265

Multi-targeted kinase inhibitor

MGCD265 targets the receptor tyrosine kinases (RTKs) Met, VEGFR 1,2,3 and Axl, as well as Tie2 and Ron. These kinases play key roles in tumor development, survival and metastasis as well as angiogenesis. Read more

MGCD516

Novel multi-target kinase inhibitor

MGCD516 targets members of the Eph receptor family, Met, Ret and VEGFR 1, 2, 3. The inclusion of Eph and Ret as targets, in addition to Met, is important due to their overexpression and/or mutation in a number of cancers. Read more

Mocetinostat

Spectrum-selective HDAC inhibitor

Mocetinostat targets a subset of class I histone deacetylases (HDACs). Inhibition of these cancer-related isoforms results in multiple and desirable anti-cancer effects. Read more

Message from Charles M. Baum, MD, PhD, President and CEO

“ I joined the Company because I recognize the value of the pipeline and the opportunity of our clinical portfolio to address unmet needs in oncology. ”

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Corporate Presentation

Corporate Presentation – February 2014

Stock Information

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