Job Opportunity

Intern, Product Development, CMC-Tech Ops

Location: San Diego, California, United States of America
Department: Technical Operations - CMC
Employment Type: Intern
Reference Number: R121

As an Intern in Product Development (PD) department, you will engage yourself into Mirati’s advanced innovative drug development program. You will work with PD leads to learn about pharmaceutical product development, formulation as well as characterization of the dosage forms using both in vitro and in vivo techniques. You will acquire understanding of methods for solubilization, tablet manufacturing, physical analysis of oral solid dosage forms, and preclinical pharmacokinetic studies. You will acquire essential expertise in designing experiments, conducting statistical analyses, and employing analytical methods. Eventually, you will develop prototypes for dog PK studies and analyze data to generate conclusions that contribute to new drug product development.    

This is an internship designed to commence in Summer 2023 full-time and may extend through the year on a part-time basis.

Your Responsibilities

  • Gain knowledge about pre-formulation, formulation development, and methods for characterizing drug products.

  • Familiarize yourself with fundamental aspects of developing oral solid dosage forms and the standard operating procedures (SOPs) that guide the development of pharmaceutical drug products.

  • Gain understanding of non-clinical animal studies for formulation screening and selection

  • Conduct literature search on enabling formulation development and characterization

  • Achieve good understanding of material sparing characterization and development techniques, biorelevant flux studies, HPLC analysis, disintegration, dissolution, flowability, particle size distribution (PSD), density, in-vitro in-vivo correlation, accelerated stability evaluation

  • Assist product development lead in manufacturing, review and generation of in vitro and in vivo characterization of lead prototypes

What is Required

  • Candidate must be a current student in good academic standing

  • Student completed at minimum upper division of undergraduate program or graduate program in the following fields: Pharmaceutical Sciences, Chemical Engineering, Pharmacy, Chemistry, Biochemistry or other life sciences related fields

  • Role will be on-site - based at Company HQ site in San Diego

  • Availability to work 40 hours/week during summer break and 15-20 hours/week during the academic year

  • Good written and verbal communication skills

Pay Disclosure

Salary Range:

$23.00 - $25.00 / hour

The salary range listed in the job posting reflects the anticipated base pay range for this role in the United States. Actual base pay decisions consider a variety of factors including, but not limited to, an individual’s skills, qualifications, and experience. In addition to a competitive base salary, this role is currently eligible for our annual discretionary bonus program and annual equity awards (roles on a sales-incentive commission plan will not be eligible for our annual discretionary bonus).